Synthetic Matrix Biology

ERC-funded project

Synthetic Biologists control cell function using assemblies of DNA parts that trigger computationally predictable behaviors.

We want to use extracellular matrix (ECM) components to control tissue and organ-level behaviors in a similar manner.

Specifically, we seek to recapitulate the early phases of human heart development using three ECM components and two cell types. 

Stock image - soon to be updated.

Contact us to find out more.

 

Cardiac Tissue Engineering

UNIPV-funded

Computational models of the heart and its tissues have been used to investigate cardiac biophysics.

 

We want to use this modeling framework to provide computer-aided design capabilities in cardiac tissue engineering.  

In collaboration with Ale Reali @ UniPV and

Alessandro Nitti e Marco De Tullio @ PoliBA.

Simulation with Cardiac Chaste.

 

©2020 by Synthetic Physiology Lab.