SYNTHETIC
PHISIOLOGY
LAB
FUNDED PROJECT
Synthetic Matrix Biology: Designer matrices to program healthy and diseased myocardial morphogenesis
ERC Starting grant
2020-2025, 2M Eur
UNLOOC: Unlocking the data content of Organ-on-Chips
EC Chips Joint Undertaking and Italian Ministry of Enterprises
2024-2027, 1M Eur
LigHTS: All-Optical Engineering of Human Tissue Models for Ultra High-Throughput Drug Screening
MUR FARE
2022-2027, 400k Eur
highLight: A competence center for bio/nano-sustainability
Regione Lombardia
2021-2023, 250k Eur
Engineered in-vitro models of cardiometabolic diseases to screen RNA-based therapeutics
EU/MUR PNRR
2022-2025, 250k Eur
RESET. REsolving infections by modulating SEnescenT macrophages
MUR PRIN 2022
2023-2025, 125k Eur
MOST RECENT SPL PAPERS
HIGHLY CITED FROM THE HARVARD DAYS
Baraglia EC, Fattorini G, Chattaraj S, Pasqualini F, Conti F.
Neurochem Res. 2025 Jun 5;50(3):181. doi: 10.1007/s11064-025-04432-9.
PMID: 40471464 Free PMC article.
Vasudevan S, Chattaraj S, Enrico A, Pasqualini FS.
Langmuir. 2025 Feb 18;41(6):3852-3864. doi: 10.1021/acs.langmuir.4c03966. Epub 2025 Feb 6.
PMID: 39913243 Free PMC article.
Current progress toward isogeometric modeling of the heart biophysics.
Torre M, Morganti S, Pasqualini FS, Reali A.
Biophys Rev (Melville). 2023 Nov 13;4(4):041301. doi: 10.1063/5.0152690. eCollection 2023 Dec.
PMID: 38510845 Free PMC article. Review.
Pasqualini F.
Biophys Rev (Melville). 2024 Mar 6;5(1):010401. doi: 10.1063/5.0203543. eCollection 2024 Mar.
PMID: 38505297 Free PMC article. No abstract available.
Chattaraj S, Torre M, Kalcher C, Stukowski A, Morganti S, Reali A, Pasqualini FS.
APL Bioeng. 2023 Dec 5;7(4):046118. doi: 10.1063/5.0166829. eCollection 2023 Dec. PMID: 38075209 Free PMC article.
Instrumented cardiac microphysiological devices via multimaterial three-dimensional printing
Johan U Lind, Travis A Busbee, Alexander D Valentine, Francesco S Pasqualini, Hongyan Yuan, Moran Yadid, Sung-Jin Park, Arda Kotikian, Alexander P Nesmith, Patrick H Campbell, Joost J Vlassak, Jennifer A Lewis, Kevin K Parker
Nature materials 16 (3), 303-308 Paperpile PDF 907 citations | 2017
Phototactic guidance of a tissue-engineered soft-robotic ray
Sung-Jin Park, Mattia Gazzola, Kyung Soo Park, Shirley Park, Valentina Di Santo, Erin L Blevins, Johan U Lind, Patrick H Campbell, Stephanie Dauth, Andrew K Capulli, Francesco S Pasqualini, Seungkuk Ahn, Alexander Cho, Hongyan Yuan, Ben M Maoz, Ragu Vijaykumar, Jeong-Woo Choi, Karl Deisseroth, George V Lauder, L Mahadevan, Kevin Kit Parker
PMID: 27387948 PMCID: PMC552633 DOI: 10.1126/science.aaf4292
A novel computational model of the human ventricular action potential and Ca transient
Eleonora Grandi, Francesco S Pasqualini, Donald M Bers
PMID: 19835882 PMCID: PMC2813400 DOI: 10.1016/j.yjmcc.2009.09.019
A tissue-engineered scale model of the heart ventricle
Luke A MacQueen, Sean P Sheehy, Christophe O Chantre, John F Zimmerman, Francesco S Pasqualini, Xujie Liu, Josue A Goss, Patrick H Campbell, Grant M Gonzalez, Sung-Jin Park, Andrew K Capulli, John P Ferrier, T Fettah Kosar,
L Mahadevan, William T Pu, Kevin Kit Parker
PMID: 31015723 PMCID: PMC6774355 DOI: 10.1038/s41551-018-0271-5
Elena Cambria, Francesco S Pasqualini, Petra Wolint, Julia Günter,
Julia Steiger, Annina Bopp, Simon P Hoerstrup, Maximilian Y Emmert
PMID: 29302353 PMCID: PMC5677990 DOI: 10.1038/s41536-017-0024-1
JetValve: Rapid manufacturing of biohybrid scaffolds for biomimetic heart valve replacement
Andrew K Capulli, Maximillian Y Emmert, Francesco S Pasqualini, Debora Kehl, Etem Caliskan, Johan U Lind, Sean P Sheehy, Sung Jin Park, Seungkuk Ahn, Benedikt Weber, Josue A Goss, Simon P Hoerstrup, Kevin Kit Parker
PMID: 28445803 PMCID: PMC5526340 DOI: 10.1016/j.biomaterials.2017.04.033