GENETIC ENGINEERING OF HUMAN CELLS

We use genetic engineering and genome editing techniques to introduce fluorescent structural and functional sensors in human cell lines and human induced pluripotent stem cells.

COMPUTATIONAL MODELING

We use both continuous and discrete modeling frameworks to study cell and tissue mechanobiology.

ENGINEERING OF CELL CULTURE PLATFORMS

We use micro/nano-fabrication and biological self-assembly to create high-throughput, high-content biomimetic platforms to study human development, health, and disease in-vitro.

FUNDED PROJECTS

1. Synthetic Matrix Biology: Designer matrices to program healthy and diseased myocardial morphogenesis
   ERC Starting grant
   2020-2025
   

2. All-Optical Engineering of Human Tissue Models for Ultra High-Throughput Drug Screening
   MUR FARE
   2022-2027
   

3. highLight: A competence center for bio/nano-sustainability
   Regione Lombardia
   2021-2023
   

4. Engineered in-vitro models of cardiometabolic diseases to screen RNA-based therapeutics
   EU/MUR PNRR
   2022-2025
   

5. RESET. REsolving infections by modulating SEnescenT macrophages (in collaboration with the Infection Dynamics Lab of Loris Rizzello at UNIMI)
   2022PL44LM
   2022-2027